Hydrocodone 10-325 mg is the chemical combination of Hydrocodone bitartrate and Acetaminophen for relief from moderate to severe pain. It contains the opioid pain reliever “hydrocodone" and a non-opioid pain reliever ‘acetaminophen’. Generally Hydrocodone works in the brain to change how your body feels and responds to pain. The Hydrocodone 10-325 mg is typically made with a combination of Acetaminophen to cure severe pain. Like Hydrocodone 10-325 mg there are other variants are available: