MicroBiotic Plus is best probiotic for IBS. It contains multiple strains that expressly target these conditions. Strains that are shown in clinical trials to help resolve these issues include: Bacillus coagulans, Lactobacillus rhamnosus, Lactobacillus plantarum, Lactobacillus acidophilus, Lactobacillus casei, Bifidobacterium longum, Bifidobacterium bifidum. These are ALL in MicroBiotic Plus.